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Patients were randomized in a 3:3:3:1:1:1 ratio to receive varying doses of semaglutide or placebo

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Gastroenterology 123 , 11201128 (2002)

This action helps reduce the blood sugar highs and lows associated with type 2 diabetes and the hunger pangs that come with low blood sugar levels

Whilst leptin replacement therapy has shown limited success in common obesity (except in rare cases of congenital leptin deficiency), alternative approaches targeting different pathways have emerged as effective therapeutic options