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Defining optimal cost-effective approaches to care, particularly in the management of patients including those with multi-morbidity is essential. They add: New questions arise from the recent cardiovascular outcomes studies

The pharmacist can assess the specific circumstances and determine if the medication remains suitable for use
Gastrointestinal side effects are common and can range from mild to severe and even life threatening

The most commonly reported effects are mild nausea, some digestive discomfort, and occasional fatigue, particularly during the first few weeks as your body adjusts to the medication

doi:10.1053/j.gastro.2025.06.003 13

The type of clot, called a deep vein thrombosis (DVT), can cause pulmonary embolisms and death or lung damage