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There are no published guidelines regarding the optimal management of pasireotide-induced hyperglycemia based on its pathophysiology

The authors are aware that this study has several limitations

John Engs research found that the saliva of the Gila monster contains a hormone that treats diabetes beter than any other medicine

His troponin and brain natriuretic peptide (BNP) levels were unremarkable

They further demonstrated that GLP-1RA dulaglutide treatment restored lysosomal function in LAMP3 overexpressing mice, thereby preventing lysosomal membrane permeability and cell death in vivo [283]

doi:10.2337/dcS13-2035 32
