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This dual-action approach is particularly valuable for people with obesity and type 2 diabetes, as it not only helps manage blood sugar but also leads to significant, sustainable weight loss

55 In this analysis utility values were applied exclusively to body weight reduction, rather than to different stages of liver disease progression, further reinforcing the conservative nature of the approach

However, concerns still remained leading to the cautionary advice issued by the FDA warning clinicians not to prescribe semaglutide to patients with a personal or family history of medullary thyroid carcinoma or patients with multiple endocrine neoplasia 2

There are no required monthly check-ins

General precautions: Retatrutide should be used only under medical supervision

New metrics and approaches better capture progress in a Retatrutide-assisted body recomposition framework