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Description
Amy Schumers weight loss with Ozempic and Mounjaro highlights the real impact of GLP-1 meds

There are now even more options available for patients who may be candidates for GLP-1 therapy

Semaglutide begins affecting hunger signals within days, but measurable weight loss typically appears between weeks 2 and 4 of treatment

DeFronzo, MD, Alan J
Mechanistically, these effects are linked to GLP-1 RA-mediated suppression of inflammatory pathways, modulation of skeletal muscle metabolism, and preservation of mitochondrial function, thereby influencing insulin resistance

Not that this has not been demonstrated before but to my surprise the questions on thyroid tumors and GLP-1 RA keep coming especially from non-endocrinologists This was a huge study that included a total of 460,032 users of GLP-1RAs, 717,792 users of SGLT2is, 2,055,583 users of DPP-4is, and 1,119,868 users of SUs GLP-1RA exposure was not associated with an increased risk of thyroid tumors compared with SGLT2is, DPP-4is, or SUs (meta-analysis: GLP-1RA vs
