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Challenges for Indian generics GLP-1 drugs such as semaglutide are peptide-based medicines that require specialized technology for production and distribution, including a cold chain for storage, making them more complex to manufacture

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For example, in the case of amylin biology, significant translational gaps between rodent and human systems persist, the optimal receptor selectivity profile for clinical use remains unclear, and molecules continue to advance in clinical development despite these uncertainties (Hollander et al., 2020)

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doi: 10.1016/j.neuropharm.2013.04.008 78 DAmicoMDi FilippoCMarfellaRAbbatecolaAMFerraraccioFRossiFet al