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[DOI] [PMC free article] [PubMed] [Google Scholar] 28.Shetty R, Basheer FT, Poojari PG, Thunga G, Chandran VP, Acharya LD

Single GLP-1 agonists activate only the GLP-1 receptor, producing effects on insulin secretion, appetite regulation, and glucose control
[3] On the other hand, Tirzepatide distinguishes itself with dual GLP-1 and GIP receptor agonism, achieving HbA1c reductions of up to 2.4% and weight loss of up to 8.8 kg at 15 mg in SURPASS trials

They can be broadly classified into two categories based on their duration of action: Short-acting formulas : These are typically taken once or twice a day

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