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The difference lies in the manufacturing quality of the powder itself
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Reduction in body weight was demonstrated in the Semaglutide Treatment Effect in People with Obesity (STEP) clinical trials

Choose your injection technique based on the amount of subcutaneous tissue present: If you can pinch at least 2.5 cm (1 inch) of skin and fat, gently pinch the thigh between your thumb and fingers to create a raised area If you have adequate subcutaneous tissue, you may inject without pinching Remove the pen cap by pulling it straight off

calc: value calculated considering reported mean baseline and mean absolute change

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