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It should not be used by individuals with a personal or family history of medullary thyroid carcinoma (a type of thyroid cancer) or those with multiple endocrine neoplasia syndrome type 2 (MEN 2)

Though with similar effects as some pre-existing drugs (semaglutide, liraglutide, exenatide, etc.) targeting diabetes and obesity, tirzepatide is considered a first-in-class medication for demonstrating action on both the glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptors

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Similar content being viewed by others Introduction In recent years, GLP-1R and its agonists have garnered widespread attention in the medical community