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Researchers, regulators, and courts have identified a range of severe health risks associated with these drugs, several of which form the basis of the lawsuits now pending against manufacturers Novo Nordisk and Eli Lilly: Gastroparesis: Also known as stomach paralysis, gastroparesis occurs when the stomach muscles weaken to the point that the stomach can no longer empty food into the small intestine at a normal rate

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Most patients find that allowing the pen or vial to sit at room temperature for 1520 minutes before injection reduces discomfort significantly

In a case-matched study of adjuvant liraglutide following retrieval of the intra-gastric balloon, there was significantly less weight regain in the liraglutide group than the placebo (1.2 kg 0.9, 0.7 1.0, p = 0.010)

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It found higher rates of wound dehiscence, delayed healing, surgical site infections, and hypertrophic (raised) scarring in the GLP-1 group