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Excellent sources include wholegrain cereals, brown rice, wholemeal bread, fruits (particularly prunes, pears, and apples with skin), vegetables, pulses, and nuts

This hormone tells your brain you are full, slows down how fast your stomach empties (gastric emptying), and prompts your pancreas to release insulin

Symptoms included bloating, discomfort in the upper abdomen, and feelings of fullness after eating

Regular monitoring, including review of symptoms, weight, HbA1c, and appropriate screening for diabetic retinopathy in those with pre-existing disease, enables early identification and management of adverse effects whilst optimising therapeutic outcomes

Interestingly, in the absence of experimental data, ADMETlab 3.0 (Fu et al., 2024) prediction suggests that SR18 has excellent blood-brain barrier (BBB) permeability (prediction probability value: 00.1), identical to that of GLP-1

In patients with HFrEF, SGLTi medications have been demonstrated to reduce the risk of either cardiovascular death or heart failure hospitalization