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In this context, GLP-1RAs can inhibit the secretion of IL-2 and interferon (IFN)-, thereby regulating the immune microenvironment and preventing diabetes [144]

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What Are GLP-1RAs, and How Do They Work

Starting doses vary by product: semaglutide typically starts at 0.25 mg weekly, dulaglutide at 0.75 mg weekly, tirzepatide at 2.5 mg weekly, while liraglutide begins at 0.6 mg daily

Important caveats include program enrollment rules, manufacturer participation, and timing of payer formulary updates that may delay savings for some patients