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Conclusions When considered collectively, GLP-1 RAs demonstrate significant potential for the treatment of age-related conditions and the extension of lifespan

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In turn, the levels of IGF-1 have been shown to be associated with an increased risk of cancer (204, 205)

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For users meaningfully lighter or cardiovascularly more responsive than the trial cohort low BMI, sub-160 lb, lean/recomposition-focused, older, or dose-sensitive the entry point drops to 0.3 mg

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Clinical trial data shows hypersensitivity reactions in approximately 3 to 13 percent of participants, compared to 3 percent in the placebo group

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