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Faisant, F

This unique mechanism produces weight loss results that surpass all currently available medications by targeting energy expenditure in addition to appetite suppression

This type of medication was originally designed to treat patients with type 2 diabetes because of their impact on insulin and blood sugar

The deceleration phase often triggers concern that something has gone wrong

The sequential nature of these steps MHRA authorisation, followed by NICE appraisal, followed by NHS commissioning means that routine NHS access to retatrutide, should it ultimately be approved, would follow a pathway similar to that of other recently authorised weight management medicines

Identify it as distinct from common obesity and pursue expert evaluation