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Mechanisms mediating the diuretic and natriuretic actions of the incretin hormone glucagon-like peptide-1

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Eur J Clin Nutr 2021;75:16841697

However GIP did not show efficacy in diabetic patients so the search continued (1)
Bupropion, an atypical antidepressant, increases dopamine and norepinephrine levels while also having mild appetite-suppressing effects

For example, high-fat foods can slow down digestion, leading to increased bloating and constipation