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However, GLP-1 agonists were not associated with an increased risk for biliary disease (HR = 1.5

Several other trials are assessing the safety and efficacy of tirzepatide in improving different cardiometabolic complications such as OSA, MASH and heart failure with preserved ejection fraction (HFpEF) (NCT05412004, NCT04166773, NCT 04847557) [16]

unpublished observations)

With a doubling in prevalence from 1980 to 2008[1], 13% of the worlds population at present are obese [body mass index (BMI) 30 kg/m 2 ] and 39% overweight (BMI 27 kg/m 2 )[2]

In contrast, Linagliptin is a long-acting drug because of its high degree of binding to dipeptidyl peptidase-4 (DPP-4)

Cinnamon extract inhibits -glucosidase activity and dampens postprandial glucose excursion in diabetic rats