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Semaglutide injections can be administered regardless of meal timing, but clinical evidence suggests fasting may optimize absorption and GI tolerability

Key points: - Weight loss in Parkinson's disease was associated w/ greater cognitive decline, whereas weight gain was associated w/ slower motor progression in previous longitudinal studies

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Compounded tirzepatide is not reviewed or approved by the FDA for safety or effectiveness

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Its growing popularity reflects increased scientific interest in multi-target peptide technologies designed to explore appetite regulation, energy expenditure, and glucose metabolism