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Impaired kidney function or dehydration can significantly increase the risk of toxicity

La deshidratacin grave puede aumentar el riesgo de lesin renal aguda, una advertencia incluida en la etiqueta de la FDA para semaglutida

10.1.3 GnRH Gonadotrophin releasing hormone is in a clinical trial of participants with Down syndrome with evidence of concomitant AD (NCT04390646)

Ultimately, compounded versions of drugs such as GLP-1s could have a place in patient treatment, but would require specific patient needs to be produced, according to Schiller

Additional considerations include the impact on weight management goals

Additionally, findings suggest that semaglutide impacts the nucleus accumbens a critical brain region tied to addiction by dampening alcohol-related reward responses
