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While effective, these treatments require monitoring due to potential side effects, especially in non-diabetic patients.This therapeutic advancement represents a revolution in the management of metabolic diseases and obesity.Despite their efficacy in managing obesity and metabolic disorders, GLP-1 and GIP receptor agonists can cause side effects, which are a common reason for therapy discontinuation

Initial research has indicated that low-dose semaglutide injections can reduce alcohol craving and some drinking outcomes, prompting calls for a larger clinical trial to evaluate GLP-1RAs for alcohol use disorder.