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, Levav, I

Miyazaki M, Kato M, Tanaka K, Tanaka M, Kohjima M, Nakamura K, et al

FIGURE 1 GLP-1R is found mainly on the cell membranes of different cell types in the human body

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16 On the other hand, the investigational use of GIPR agonists (GIPRAs) has not yielded similar advantages, partly because of a lack of understanding of GIP dose-response actions

Notably, kidney and cardiovascular benefits of finerenone were apparent even in combination with SGLT2i and GLP1-RA use in secondary analyses of the FIDELIO-DKD and FIGARO-DKD trials [71, 72]