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Here, the authors show that remote ischaemic preconditioning releases the gut hormone GLP-1, which relaxes cardiac pericytes via KATP channels to reduce capillary constriction and no-reflow.

India Issues Urgent GLP-1 Drug Safety Alert The Indian Pharmacopoeia Commission (IPC) has issued a public notice on 14 May calling on doctors, patients, and consumers to closely monitor and report any adverse reactions linked to semaglutide and other GLP-1 receptor agonists including dulaglutide, liraglutide, and tirzepatide

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Understand their differences in efficacy and safety.

Tirzepatide displayed an unprecedented glucose and body weight lowering potential, presenting also with the ability to increase insulin sensitivity, reduce systolic blood pressure and inflammation and ameliorate dyslipidemia, particularly by reducing triglycerides levels