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Significance of the Topic The emergence of glucagon-like peptide-1 (GLP-1) receptor agonists, particularly semaglutide, has transformed treatment strategies

But from a neuropathology perspective, the evidence is thin

We aimed to investigate these mechanisms using an in vitro model of steatosis treated with the GLP-1R agonist Exendin-4 (Ex-4)

To our knowledge, this is the first reported case suggesting the potential role of GLP-1 receptor agonists in slowing the progression of localized scleroderma, possibly due to their anti-fibrotic and anti-inflammatory effects.

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acidophilus, help balance the gut microbiome, enhance nutrient absorption, and promote long-term digestive comfort