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The machinery it drives inside the cell maxes out long before the receptor itself fills, so the effect can run flat-out while occupancy is still tiny (the spare-receptor effect)

Lancet 2009;373:2125-2135

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With Wegovy, interactions can happen because the medicine: Slows your stomach emptying Changes your appetite and eating patterns Affects the regulation of your blood sugar Can lead to nausea, vomiting, or diarrhoea When your digestion slows down, some of the oral medicines you are taking may take longer to absorb by your body

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