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Results can vary depending on: Dosage Consistency Metabolism Sleep quality Nutrition Exercise habits Overall health In many cases: Sleep and recovery improvements may appear earlier Body composition changes usually take longer Tesamorelin body composition effects are often discussed within a several-month timeframe

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This accelerated decay often occurs even in patients with previously stable oral health and good hygiene habits

Suitability considerations: Consistent with class precedents for GLP-1-based therapies, retatrutide would not be expected to be suitable during pregnancy or breastfeeding, and paediatric data are currently lacking

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and the mean BMI was 41.5 kg/m2 (range: 24.4-66.1 kg/m2) at baseline