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The decision integrates objective clinical data, patient-reported outcomes, safety considerations, and individualized treatment goals

Semaglutide is a GLP-1 receptor agonist that works by supporting the body's natural appetite-regulating mechanisms

however, the result remains shortterm and imprecise and should not be interpreted as establishing a durable or independent glycaemic effect

While most current therapies do not directly address the primary drivers of molecular damage, some appear to influence downstream pathways that shape metabolic regulation, inflammatory signaling, and mitochondrial function
