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Although Genfit will continue to develop Elafibranor for the treatment of PBC, the company has decided to terminate its Phase 3 RESOLVE-IT trial
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Importantly, preclinical studies have demonstrated that co-administration of GIP and GLP-1 intracerebroventricularly results in an additive enhancement in weight-lowering efficacy (138)

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Muscle tissue is metabolically expensive, meaning the body will shed it to save energy unless there is a demand placed upon it