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If the vial has been frozen accidentally, discard it and obtain a replacement

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Not direct ice Keep the medication in its box Check that the cooler stays between 46F77F Carry it in hand luggage for better control Never store it in a checked bag or leave it in a parked vehicle
The strongest approvals align with a consistent headache diary, clear diagnosis, and adherence to the 12-week schedule, because gaps can be interpreted as lack of medical necessity
