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The core peptide was released from the His 6 -tagged leader by 1:20 addition of LahT150 protease (containing 1 mM DTT) for 2 h at 37 C

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Indeed, albuminuria and reduced kidney function have been addressed as partially responsible for the residual CV risk persisting despite correction of common CV risk factors 79

The decision is based on a cluster of weak trust signals, not one isolated event