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Diabetes-related chronic inflammatory state can therefore produce progressive qualitative damage of myocardial tissue resulting in progressive left ventricular, either systolic or diastolic, functional impairment

This reduces the risk of hypoglycaemia compared to some other diabetes medicines, though the risk increases when used alongside insulin or sulfonylureas

Contributions of fasting and postprandial plasma glucose increments to the overall diurnal hyperglycemia of type 2 diabetic patients: variations with increasing levels of HbA(1c)
That is the difference between losing 20 pounds and losing 27

For depression, tirzepatide showed a 65% reduced risk versus 45% for semaglutide

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