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Serious adverse effects are uncommon when dosing is appropriate and therapy is supervised, but ongoing monitoring and periodic labs are recommended to watch for shifts in glucose, fluid balance, or hormone sensitivity

Notably, more than one-third of participants achieved weight loss of 25% or greater, results previously seen only with bariatric surgery

Lancet 2018;392:1519-29

[DOI] [PubMed] [Google Scholar] 18.Capehorn M.S., Catarig A.M., Furberg J.K., et al

Hormonal Regulation of Appetite and Metabolism in Women

Role of Intestinal Microbiota in the Bioavailability and Physiological Functions of Dietary Polyphenols