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Compared to other weight loss drugs, using GLP-1 agonists increases the risk of pancreatitis (inflammation of the pancreas) by 9 times, bowel obstruction (blockage of the small or large intestines) by 4.5 times, and gastroparesis (a condition that slows or stops the movement of food from the stomach to the small intestine) by 3.6 times

Our programs may incorporate body scans, comprehensive blood work, and nutritional counseling, and may also include prescription medications, including GLP-1s

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In this episode and the accompanying feature, we invited a patient with lived experience to see if this worked in real life while discussing the potential mechanisms with a researcher.

Although glycogen synthesis and intracellular glycogen levels proportionally inhibit AMPK activity [86], the increase in glycogen seen in patients receiving GLP-1 agonists may be partially due to GLP-1R/AMPK activation that overrides basal glycogen inhibition of AMPK

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