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Description
Comparative efficacy of glucagon-like peptide 1 (GLP-1) receptor agonists, pioglitazone and vitamin E for liver histology among patients with nonalcoholic fatty liver disease: systematic review and pilot network meta-analysis of randomized controlled trials

While on the medication, people often describe a quieting of food noise, the constant mental hum of negotiating cravings and thinking about the next opportunity to eat

Lower cost GLP-1 medications for other populations is likely to lead to some relief from the high cost of these medications
One review showed that people lost about 4 lbs when taking berberine regularly (500 mg daily)

Given all these unknowns, it may be best for Congress to pump the brakes on expanding GLP-1s in Medicare before we have a better understanding of their full value and a way to pay for it.

Previously described cardiovascular effects of GLP-1 RAs are primarily indirect and include enhanced endothelial function and myocardial metabolism, natriuresis and anti-inflammatory and blood pressure-lowering effects