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### Funding Statement SDL and AC were supported by the National Science Foundation (Grant Nos.\ CAREER DMS-1944574 and DMS-2325258) ### Author Declarations I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained

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Tirzepatide restored the aberrant levels of acetylcholine, A1-42, and pTau proteins, major AD hallmarks

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