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The efficacy estimand will be evaluated on the efficacy analysis set (EAS) which is based on the mITT for efficacy analyses population excluding data after treatment discontinuation, initiation of other OMMs, GLP1 receptor agonists, GIP/GLP1 receptor agonists, DPP4 inhibitors, or rescue tirzepatide, or having bariatric surgery or other weightloss procedures

Ensure adequate protein intake and include iron-rich foods or vitamin D sources if levels are low

A reasonable tapering approach would involve stepping down by one dose tier every four weeks

Tirzepatide : In a 72-week study, people taking tirzepatide lost an average of 21% of their body weight

Has there been more diversity with medicines like Zepbound

helps by offering structured medical support throughout