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call 988 Suicide & Crisis Lifeline) Your provider may recommend adjusting your dose, extending the titration schedule, or adding mental health support

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This makes it a particularly logical addition for people transitioning off tirzepatide or semaglutide who want to maintain some GLP-1 pathway support without the full potency and cost of injectable GLP-1 agonists

Large cardiovascular outcome trials, including LEADER (liraglutide), SUSTAIN-6 (semaglutide), and REWIND (dulaglutide), have demonstrated cardiovascular risk reduction with GLP-1 receptor agonists

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