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Description
Most patients begin to notice reduced appetite and improved portion control within the first few weeks of oral GLP-1 therapy
A total of 54% were Hispanic or Latino ethnicity
For those who remained on the drug, weight loss slowed considerably and by the end, had started to rise slightly, which means that the claim that weight loss will be permanent as long as people stay on the drug is not supported by the evidence
At the same time, postmarketing experience, case reports, and anecdotal clinic observations have described mood changes after starting Tirzepatide
Food and Drug Administration (FDA) in May 2022
The glucagon receptor activation is the key driver of this liver benefit
