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2023;8(10) doi: 10.1172/jci.insight.164921

Analysis of the ability of pramlintide to inhibit amyloid formation by human islet amyloid polypeptide reveals a balance between optimal recognition and reduced amyloidogenicity

CYP-mediated metabolism plays a central role in many CNS interactions

He kept the weight off through college and during the early years of marriage

Last month, Novo Nordisk won Food and Drug Administration approval for the first GLP-1 pill for weight loss

Clinical trials are designed around percent body weight reduction, achievement of predefined thresholds such as 10 or 15 percent loss, and improvements in obesity-related comorbidities
