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1 Introduction Metformin is a synthetic derivative of guanidine derived from the guanidine alkaloid of the plant named Galega officinalis L

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GLP-1 receptors are found throughout the body, including inside the brain, where they are connected to pathways involving reward, stress and impulse control

References: Collins L, Costello RA

Among the various HFpEF phenotypes identified, the obesity-related phenotype characterized by visceral adiposity and insulin resistance appears to be the most prevalent (92)

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