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Tirzepatide, with its dual action as both a GLP-1 and GIP receptor agonist, might be more potent at lower doses compared to semaglutide, which acts only on the GLP-1 receptor
The global GLP-1 market is estimated to grow from USD 49.3 billion in the current year to USD 157
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In conclusion, the paper provides evidence that the reduction of GLP-1+ cells is a general feature of ileal and colonic inflammation in mice and humans and is likely due to altered epithelial differentiation driven by changes in cellular metabolism, particularly mitochondrial dysfunction.
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