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NICE has approved tirzepatide for type 2 diabetes in adults with inadequate glycaemic control (TA848) and for weight management in adults with a BMI of at least 35 kg/m (or at least 30 kg/m with weight-related comorbidities) who have high cardiovascular risk (TA946)

Most patients start with T10 during their first 812 weeks, then transition to T50 once at therapeutic doses

Possible side effects include increased hunger, mood changes, and digestion issues