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They currently appear to be best in class for cardiovascular risk reduction and HFpEF [ heart failure with preserved ejection fraction] reduction in hospitalizations, [with a] 35% reduction in the risk of stroke in those with type 2 [diabetes]. Jayne Morgan, MD The meta-analysis found that oral semaglutide was superior to the subcutaneous version at reducing all-cause mortality

If you experience severe or persistent vomiting that prevents you from keeping fluids down, severe abdominal pain, or any symptoms that feel like more than standard GI distress, contact your healthcare provider or go to the emergency room

No significant changes were observed in the placebo group across the 26-week period

Additional known effects include cholelithiasis, modest heart rate increase of 2-4 bpm, and a boxed warning for thyroid C-cell tumors

Nutrient Balance While protein is essential, its crucial to maintain a balanced diet that includes a variety of food groups