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La efectividad del tratamiento se determin midiendo el tiempo transcurrido entre el inicio de la terapia y la aparicin del primer evento cardiovascular mayor (MACE, por sus siglas en ingls), que incluye muerte cardiovascular, infarto de miocardio no mortal y accidente cerebrovascular no mortal

A notable observation from the findings was the dose-related response, where lower dosages were associated with more effective and stable reductions in HbA1c, an important insight for treatment planning

IGF-1/IGF1R signaling has also been associated with Schwann cell (SC) survival, migration, proliferation, and myelination [29, 30]

16 and 17, respectively) were used

The trial reported substantial weight reduction approximately 24% of body weight at the highest dose over 48 weeks and confirmed that gastrointestinal adverse events were the most frequently reported side effects

Jairo Norea, a former endocrinology fellow at Stanford University Medical Center in Palo Alto, Calif