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People with a history of pancreatitis, significant gastrointestinal disease, advanced kidney or liver disease, or specific endocrine tumors may not be candidates for Tirzepatide

10.1038/414813a 2 BuseJ

The Evolving Story: Why Dual Agonism Isn't the Final Word The metabolic landscape shifted dramatically when Tirzepatide , a first-in-class dual GIP and GLP-1 receptor agonist, received FDA approval

But specific populations face unique considerations that deserve separate discussion

Always check the specific storage instructions from your pharmacy

Once the 21 days are up, the syringe must be discarded, even if it went back into refrigeration and even if it was never used