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In vivo and in vitro Studies All animals were randomized into their respective treatment groups based on body weight and were males between 812 weeks age

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Current surveillance has not demonstrated a substantial rise in cases linked to GLP-1 therapies

40 Currently, they can be used to treat hypertriglyceridemia in NASH but not for the treatment of NAFLD or NASH

Despite lower efficacy and tolerability shown by nasally administered PYY agonists in early studies, long-acting subcutaneous PYY receptor agonists such as PYY 1875 are undergoing early-phase clinical trials to evaluate their safety and effectiveness as monotherapy or in combination with GLP-1 receptor agonists for the treatment of obesity

Mounjaro Al igual que Ozempic, Mounjaro se desarroll originalmente para tratar la diabetes tipo 2, pero actualmente tambin est autorizado de forma oficial como tratamiento para la prdida de peso