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The graph below visually represents the increasing cost per member per month (PMPM) for GLP-1 medications between 2022 and 2024 with the predicted increase for 2025

Mice without MRS2 stayed lean, despite eating similar amounts of food, drinking similar amounts of water, and moving about as much as the other animals

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This suggests that starting with lower doses and smaller dose increments is associated with a more favorable side effect profile

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For example, if you want to move from Thursday to Tuesday, you might take your next injection on Tuesday (5 days early), then establish Tuesday as your new weekly day going forward