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Its role exhibits context-dependent duality, functioning as a cytoprotective mechanism or contributing to regulated cell death (Levine and Kroemer, 2019)

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The FDAs decision was supported by data from the Phase II ROSEWOOD trial, in which the BrukinsaGazyva combo led to a 69% overall response rate (ORR) compared to 46% ORR in patients treated with Gazyva alone, according to BeiGene

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TABLE 1 Current clinical studies and trials studying GLP-1RAs effect on various eye diseases

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