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Lets look at the actual numbers from the SURPASS clinical trial program the largest trials ever done on a diabetes drug: To put this in perspective most diabetes drugs reduce HbA1c by 0.51%

What are the potential issues with the program

Overfilling makes the lid harder to seal and increases puncture risk during handling

Standard Retatrutide Dosage Chart The non-split Phase 2 titration chart for once-weekly dosing

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Oshis team understands what patients struggling with GI symptoms, including those taking GLP-1s, need: Integrated multidisciplinary care: Patients should receive coordinated care addressing each of their needs, with support from GI providers for diagnosis and medication, registered dietitians to pair GLP-1s with the right diet for sustainable improvement, behavioral health specialists to ease the anxiety around GLP-1 side effects for adherence, and care coordinators to work with their existing GLP-1 provider