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Nevertheless, the starting dose of the new GLP-1 receptor agonist can be adjusted to minimize the potential for such increases (Figure 2)

All components of the main kidney 5-composite endpoint were adjudicated by an independent expert committee blinded to treatment status

It also helps identify patterns that might not be obvious otherwise

Figure 2a: From step 1 (left) to steps 2 and 3 (right)

Thats a fundamental principle in medicine. She warned that sensationalised warnings or blanket statements against semaglutide could do more harm than good

GLP-1s help the kidneys release more sodium into the urine, which reduces fluid buildup in the bloodstream and eases pressure on blood vessels
