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Although our patient received tirzepatide, it belongs to a similar drug class as semaglutide

The second NPC approval in a week highlights the FDAs commitment to supporting the development of innovative therapies for rare diseases, Janet Maynard, director of the FDAs Office of Rare Diseases, Pediatrics, Urologic and Reproductive Medicine, said in a statement

Tirzepatide accomplishes this without the urinary glucose spillage that defines SGLT2 inhibitor therapy

JACS Au 2 , 10071017 (2022)

who observed preservation of glomerular filtration rate, increase in stroke volume, and enhancement of the inotropic effect of exogenous brain natriuretic peptide due to DPP-4 inhibition [77]

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