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In this study, unlike previous studies using non-diabetic animals, we demonstrated using diabetic model rats and confocal laser scanning microscopy that the GLP-1/GLP-1R complex was located in the endosome of diabetic islets

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As a receptor agonist, GLP-SG enables researchers to study how activation of a single incretin pathway influences intracellular signaling cascades, receptor pharmacology, and metabolic processes across tissues such as the pancreas, liver, and adipose tissue

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